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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADAMTS6 All Species: 25.45
Human Site: T453 Identified Species: 56
UniProt: Q9UKP5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKP5 NP_922932.2 1117 125273 T453 A C S R D Y I T S F L D S G R
Chimpanzee Pan troglodytes XP_526907 1117 125238 T453 A C S R D Y I T S F L D S G R
Rhesus Macaque Macaca mulatta XP_001084793 1117 125301 T453 A C S R D Y I T S F L D S G R
Dog Lupus familis XP_535255 1117 125043 T453 A C S R D Y I T S F L D S G R
Cat Felis silvestris
Mouse Mus musculus P58459 1104 121067 S447 Y I T S F L D S G L G L C L N
Rat Rattus norvegicus Q1EHB3 1595 175796 S642 P C Y Q G R I S R D I C I D G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513889 903 100601 D260 V E T L V V A D K M M V G Y H
Chicken Gallus gallus XP_424749 1118 125075 T454 A C S R D Y I T S F L D S G R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923204 1116 124633 T452 A C S K D Y I T S F L D S G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19791 2150 242563 R483 E R F L E N N R G Q T Q C L F
Sea Urchin Strong. purpuratus XP_001180742 1320 148448 S570 C S A H Y I T S Y I E S G K A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.6 98.4 N.A. 59.7 30.4 N.A. 72.9 92.4 N.A. 82.8 N.A. N.A. N.A. 21.4 39.7
Protein Similarity: 100 99.9 99.7 98.9 N.A. 74.4 41.5 N.A. 75.7 95.8 N.A. 90.1 N.A. N.A. N.A. 31.1 54.6
P-Site Identity: 100 100 100 100 N.A. 0 13.3 N.A. 0 100 N.A. 93.3 N.A. N.A. N.A. 0 0
P-Site Similarity: 100 100 100 100 N.A. 13.3 33.3 N.A. 13.3 100 N.A. 100 N.A. N.A. N.A. 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 55 0 10 0 0 0 10 0 0 0 0 0 0 0 10 % A
% Cys: 10 64 0 0 0 0 0 0 0 0 0 10 19 0 0 % C
% Asp: 0 0 0 0 55 0 10 10 0 10 0 55 0 10 0 % D
% Glu: 10 10 0 0 10 0 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 10 0 10 0 0 0 0 55 0 0 0 0 10 % F
% Gly: 0 0 0 0 10 0 0 0 19 0 10 0 19 55 10 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 10 0 0 0 10 64 0 0 10 10 0 10 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 10 0 0 0 0 10 0 % K
% Leu: 0 0 0 19 0 10 0 0 0 10 55 10 0 19 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 10 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 10 0 10 0 0 0 % Q
% Arg: 0 10 0 46 0 10 0 10 10 0 0 0 0 0 55 % R
% Ser: 0 10 55 10 0 0 0 28 55 0 0 10 55 0 0 % S
% Thr: 0 0 19 0 0 0 10 55 0 0 10 0 0 0 0 % T
% Val: 10 0 0 0 10 10 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 10 0 10 55 0 0 10 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _